| Tissue Specificity | Ubiquitous. Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary. Expressed in astrocytes. |
| Function | Calcium-binding protein. Binds one calcium ion per monomer. Can promote differentiation of adipocytes (in vitro). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake. |
| Protein Name | Protein S100-A16Aging-Associated Gene 13 ProteinProtein S100-FS100 Calcium-Binding Protein A16 |
| Cellular Localisation | NucleusNucleolusCytoplasmPrimarily NucleolarA High Intracellular Calcium Level Induces Nucleolar Exit And Nucleocytoplasmic TransportWhereas A Low Intracellular Calcium Level Leads To Nuclear Translocation And Accumulation Within Specific Region Of Nucleoli |
| Alternative Antibody Names | Anti-Protein S100-A16 antibodyAnti-Aging-Associated Gene 13 Protein antibodyAnti-Protein S100-F antibodyAnti-S100 Calcium-Binding Protein A16 antibodyAnti-S100A16 antibodyAnti-S100F antibodyAnti-AAG13 antibody |
Information sourced from Uniprot.org
