Anti-RYR3 antibody (C-Term) (STJ13101952)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from c-terminal region of human Ryanodine receptor 3 (RYR3) conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-RYR3 (C-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | RYR3 |
| Gene ID | 6263 |
| Uniprot ID | RYR3_HUMAN |
| Immunogen | A synthetic peptide from c-terminal region of human Ryanodine receptor 3 (RYR3) conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | C-Term |
| Specificity | Specific for RYR3. |
Additional Info
| Function | Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis. Plays a role in cellular calcium signaling. |
| Protein Name | Ryanodine Receptor 3Ryr-3Ryr3Brain Ryanodine Receptor-Calcium Release ChannelBrain-Type Ryanodine ReceptorType 3 Ryanodine Receptor |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-5578775 |
| Cellular Localisation | Sarcoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ryanodine Receptor 3 antibodyAnti-Ryr-3 antibodyAnti-Ryr3 antibodyAnti-Brain Ryanodine Receptor-Calcium Release Channel antibodyAnti-Brain-Type Ryanodine Receptor antibodyAnti-Type 3 Ryanodine Receptor antibodyAnti-RYR3 antibodyAnti-HBRR antibody |
Information sourced from Uniprot.org