Anti-RXR beta antibody (Internal) (STJ70606)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-RXR beta (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 55kDa band observed in lysates of cell line A431 (calculated MW of 56.9kDa according to NP_068811.1). In transfected HEK293 transiently expressing RXRB a band of approx. 60kDa |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | RXRB |
| Gene ID | 6257 |
| Uniprot ID | RXRB_HUMAN |
| Accession Number | NP_068811.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | CRDGMGDSGRDSRSP |
| Specificity | This antibody is expected to recognise an epitope corresponding to aa 70-83 of human RXR beta protein and does not cross-react with either RXR alpha or gamma. |
Additional Info
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE). |
| Protein Name | Retinoic Acid Receptor Rxr-BetaNuclear Receptor Subfamily 2 Group B Member 2Retinoid X Receptor Beta |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-9029558Reactome: R-HSA-9029569Reactome: R-HSA-9031525Reactome: R-HSA-9031528Reactome: R-HSA-9623433Reactome: R-HSA-9632974 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Beta antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 2 antibodyAnti-Retinoid X Receptor Beta antibodyAnti-RXRB antibodyAnti-NR2B2 antibody |
Information sourced from Uniprot.org