Anti-RUNX1T1 antibody (STJA0007721)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RUNX1T1
General Information
| Short Description | Rabbit polyclonal anti-Protein CBFA2T1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RUNX1T1 |
| Gene ID | 862 |
| Uniprot ID | MTG8_HUMAN |
| Immunogen | Synthesized peptide derived from human RUNX1T1 |
| Specificity | This antibody detects endogenous levels of RUNX1T1 at Human, Mouse |
Additional Info
| Function | Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12. Acts as a negative regulator of adipogenesis. The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal. |
| Protein Name | Protein Cbfa2t1Cyclin-D-Related ProteinEight Twenty One ProteinProtein EtoProtein Mtg8Zinc Finger Mynd Domain-Containing Protein 2 |
| Database Links | |
| Cellular Localisation | NucleusColocalizes With Atn1 In Discrete Nuclear Dots |
| Alternative Antibody Names | Anti-Protein Cbfa2t1 antibodyAnti-Cyclin-D-Related Protein antibodyAnti-Eight Twenty One Protein antibodyAnti-Protein Eto antibodyAnti-Protein Mtg8 antibodyAnti-Zinc Finger Mynd Domain-Containing Protein 2 antibodyAnti-RUNX1T1 antibodyAnti-AML1T1 antibodyAnti-CBFA2T1 antibodyAnti-CDR antibodyAnti-ETO antibodyAnti-MTG8 antibodyAnti-ZMYND2 antibody |
Information sourced from Uniprot.org