| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-RUFY1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.05-0.2µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
RUFY1 |
| Gene ID: |
80230 |
| Uniprot ID: |
RUFY1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_079434.3; NP_001035541.1 |
| Specificity: |
This antibody is expected to recognize both reported isoforms (NP_079434.3; NP_001035541.1). Reported variants represent identical protein: NP_001035542.1, NP_001035541.1. |
| Immunogen Sequence: |
QKNEAITSFEGKT |
| Post Translational Modifications | Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting. |
| Function | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. |
| Protein Name | Run And Fyve Domain-Containing Protein 1Fyve-Finger Protein Eip1La-Binding Protein 1Rab4-Interacting ProteinZinc Finger Fyve Domain-Containing Protein 12 |
| Database Links | Reactome: R-HSA-1660499 |
| Cellular Localisation | CytoplasmEarly Endosome MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Run And Fyve Domain-Containing Protein 1 antibodyAnti-Fyve-Finger Protein Eip1 antibodyAnti-La-Binding Protein 1 antibodyAnti-Rab4-Interacting Protein antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 12 antibodyAnti-RUFY1 antibodyAnti-RABIP4 antibodyAnti-ZFYVE12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
