| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RNA transcription, translation and transport factor protein (29-79) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RTRAF |
| Gene ID: |
51637 |
| Uniprot ID: |
RTRAF_HUMAN |
| Immunogen Region: |
29-79 |
| Specificity: |
This antibody detects endogenous levels of human CN166 |
| Immunogen: |
Synthesized peptide derived from human CN166 AA range: 29-79 |
| Function | RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport. (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication. |
| Protein Name | Rna Transcription - Translation And Transport Factor ProteinCle7 HomologCleHcle |
| Database Links | Reactome: R-HSA-6784531 |
| Cellular Localisation | NucleusCytoplasmCytosolPerinuclear RegionCytoskeletonMicrotubule Organizing CenterCentrosomeMay Localize At The Centrosome During MitosisShuttles Between The Cytosol And The Nucleus: Enters Into The Nucleus In Case Of Active Transcription While It Accumulates In Cytosol When Transcription Level Is Low(Microbial Infection) Following Influenza A Virus (Iav) InfectionIncluded In Influenza A Virions Via Its Association With Packaged Viral Ribonucleoproteins (Vrnp) In The Nucleus And Cytoplasm |
| Alternative Antibody Names | Anti-Rna Transcription - Translation And Transport Factor Protein antibodyAnti-Cle7 Homolog antibodyAnti-Cle antibodyAnti-Hcle antibodyAnti-RTRAF antibodyAnti-C14orf166 antibodyAnti-CGI-99 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
