Anti-RTN2 antibody (391-440 aa) (STJ192569)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 391-440
General Information
| Short Description | Rabbit polyclonal anti-Reticulon-2 (391-440 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RTN2 |
| Gene ID | 6253 |
| Uniprot ID | RTN2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 391-440 |
| Immunogen Region | 391-440 aa |
| Specificity | RTN2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface. Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell. |
| Protein Name | Reticulon-2Neuroendocrine-Specific Protein-Like 1Nsp-Like Protein 1Neuroendocrine-Specific Protein-Like INsp-Like Protein INspli |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinSarcoplasmic Reticulum MembraneCell MembraneSarcolemmaT-TubuleCytoplasmMyofibrilSarcomereZ LineCytoskeletonLocalizes To Intermediate Filaments In Mononucleated Myoblasts And To Z Lines In Mature Myotubes |
| Alternative Antibody Names | Anti-Reticulon-2 antibodyAnti-Neuroendocrine-Specific Protein-Like 1 antibodyAnti-Nsp-Like Protein 1 antibodyAnti-Neuroendocrine-Specific Protein-Like I antibodyAnti-Nsp-Like Protein I antibodyAnti-Nspli antibodyAnti-RTN2 antibodyAnti-NSPL1 antibody |
Information sourced from Uniprot.org