Anti-RTN2 antibody (391-440 aa) (STJ192569)

SKU:
STJ192569
€60.00 - €315.00
Processing The item has been added

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Reticulon-2 (391-440 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RTN2
Gene ID: 6253
Uniprot ID: RTN2_HUMAN
Immunogen Region: 391-440 aa
Specificity: RTN2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 391-440
Function Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface. Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell.
Protein Name Reticulon-2
Neuroendocrine-Specific Protein-Like 1
Nsp-Like Protein 1
Neuroendocrine-Specific Protein-Like I
Nsp-Like Protein I
Nspli
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Sarcoplasmic Reticulum Membrane
Cell Membrane
Sarcolemma
T-Tubule
Cytoplasm
Myofibril
Sarcomere
Z Line
Cytoskeleton
Localizes To Intermediate Filaments In Mononucleated Myoblasts And To Z Lines In Mature Myotubes
Alternative Antibody Names Anti-Reticulon-2 antibody
Anti-Neuroendocrine-Specific Protein-Like 1 antibody
Anti-Nsp-Like Protein 1 antibody
Anti-Neuroendocrine-Specific Protein-Like I antibody
Anti-Nsp-Like Protein I antibody
Anti-Nspli antibody
Anti-RTN2 antibody
Anti-NSPL1 antibody

Information sourced from Uniprot.org