Anti-RTN1 antibody (STJA0007353)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RTN1 (Isoform RTN1-C)
General Information
| Short Description | Rabbit polyclonal anti-Reticulon-1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RTN1 |
| Gene ID | 6252 |
| Uniprot ID | RTN1_HUMAN |
| Immunogen | Synthesized peptide derived from human RTN1 (Isoform RTN1-C) |
| Specificity | This antibody detects endogenous levels of RTN1 (Isoform RTN1-C) at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Isoforms RTN1-A and RTN1-B are phosphorylated. |
| Function | Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. |
| Protein Name | Reticulon-1Neuroendocrine-Specific Protein |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Reticulon-1 antibodyAnti-Neuroendocrine-Specific Protein antibodyAnti-RTN1 antibodyAnti-NSP antibody |
Information sourced from Uniprot.org