Anti-RRM2 antibody (260-310) (STJA0006644)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RIR2 AA range: 260-310
General Information
| Short Description | Rabbit polyclonal anti-Ribonucleoside-diphosphate reductase subunit M2 (260-310) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RRM2 |
| Gene ID | 6241 |
| Uniprot ID | RIR2_HUMAN |
| Immunogen | Synthesized peptide derived from human RIR2 AA range: 260-310 |
| Immunogen Region | 260-310 |
| Specificity | This antibody detects endogenous levels of human RIR2 |
Additional Info
| Function | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling. |
| Protein Name | Ribonucleoside-Diphosphate Reductase Subunit M2Ribonucleotide Reductase Small ChainRibonucleotide Reductase Small Subunit |
| Database Links | Reactome: R-HSA-499943Reactome: R-HSA-69205Reactome: R-HSA-8953750 |
| Cellular Localisation | CytoplasmNucleusLocalized To The Cytoplasm In S Phase CellsMay Localize To The Nucleus In G2 Phase Cells |
| Alternative Antibody Names | Anti-Ribonucleoside-Diphosphate Reductase Subunit M2 antibodyAnti-Ribonucleotide Reductase Small Chain antibodyAnti-Ribonucleotide Reductase Small Subunit antibodyAnti-RRM2 antibodyAnti-RR2 antibody |
Information sourced from Uniprot.org