Anti-RRM1 antibody (691-792) [S7MR] (STJ11102027)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal RRM1 (691-792) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RRM1 |
| Gene ID | 6240 |
| Uniprot ID | RIR1_HUMAN |
| Immunogen Region | 691-792 |
| Immunogen Sequence | VLKMAAERGAFIDQSQSLNI HIAEPNYGKLTSMHFYGWKQ GLKTGMYYLRTRPAANPIQF TLNKEKLKDKEKVSKEEEEK ERNTAAMVCSLENRDECLMC GS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 691-792 of human RRM1 (P23921). |
Additional Info
| Function | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. |
| Protein Name | Ribonucleoside-Diphosphate Reductase Large SubunitRibonucleoside-Diphosphate Reductase Subunit M1Ribonucleotide Reductase Large Subunit |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ribonucleoside-Diphosphate Reductase Large Subunit antibodyAnti-Ribonucleoside-Diphosphate Reductase Subunit M1 antibodyAnti-Ribonucleotide Reductase Large Subunit antibodyAnti-RRM1 antibodyAnti-RR1 antibody |
Information sourced from Uniprot.org