Anti-RRAS antibody [R06-7A2] (STJA0034825)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human RRAS
General Information
| Short Description | Rabbit monoclonal anti-RRAS for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-7A2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | RRAS |
| Gene ID | 6237 |
| Uniprot ID | RRAS_HUMAN |
| Immunogen | A synthetic peptide of human RRAS |
Additional Info
| Post Translational Modifications | S-palmitoylated by ZDHHC19, leading to increased association with membranes and with rafts/caveolae as well as enhanced cell viability. |
| Function | GTP-binding protein with GTPase activity, likely involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes. Regulates the organization of the actin cytoskeleton. With OSPBL3, modulates integrin beta-1 (ITGB1) activity. |
| Protein Name | Ras-Related Protein R-RasP23 |
| Database Links | Reactome: R-HSA-399955Reactome: R-HSA-416550 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideInner Surface Of Plasma Membrane Possibly With Attachment Requiring Acylation Of The C-Terminal Cysteine (By Similarity With Ras) |
| Alternative Antibody Names | Anti-Ras-Related Protein R-Ras antibodyAnti-P23 antibodyAnti-RRAS antibody |
Information sourced from Uniprot.org