| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPS27 |
| Gene ID: | 6232 |
| Uniprot ID: | RS27_HUMAN |
| Immunogen Region: | 1-84 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-84 of human RPS27 (NP_001021.1). |
| Immunogen Sequence: | MPLAKDLLHPSPEEEKRKHK KKRLVQSPNSYFMDVKCPGC YKITTVFSHAQTVVLCVGCS TVLCQPTGGKARLTEGCSFR RKQH |
| Tissue Specificity | Expressed in a wide variety of actively proliferating cells and tumor tissues. |
| Function | Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for proper rRNA processing and maturation of 18S rRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Small Ribosomal Subunit Protein Es2740s Ribosomal Protein S27Metallopan-Stimulin 1Mps-1 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-6791226Reactome: R-HSA-68877Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9648025Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | CytoplasmNucleusNucleolus |
| Alternative Antibody Names | Anti-Small Ribosomal Subunit Protein Es27 antibodyAnti-40s Ribosomal Protein S27 antibodyAnti-Metallopan-Stimulin 1 antibodyAnti-Mps-1 antibodyAnti-RPS27 antibodyAnti-MPS1 antibody |
Information sourced from Uniprot.org