Anti-RPRD1A antibody (47-276) (STJ118299)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RPRD1A (47-276) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPRD1A |
| Gene ID | 55197 |
| Uniprot ID | RPR1A_HUMAN |
| Immunogen Region | 47-276 |
| Immunogen Sequence | PVIVEAFKHVSSETDESCKK HLGRVLSIWEERSVYENDVL EQLKQALYGDKKPRKRTYEQ IKVDENENCSSLGSPSEPPQ TLDLVRALQDLENAASGDAA VHQRIASLPVEVQEVSLLDK ITDKESGERLSKMVEDACML LADYNGRLAAEIDDRKQLTR MLADFLRCQKEALAEKEHKL EEYKRKLARVSLVRKELRSR IQSLPDLSRLPNVTGSHMHL PFAGDIYSED |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 47-276 of human RPRD1A (NP_001290341.1). |
Additional Info
| Function | Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. |
| Protein Name | Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1aCyclin-Dependent Kinase Inhibitor 2b-Related ProteinP15ink4b-Related Protein |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1a antibodyAnti-Cyclin-Dependent Kinase Inhibitor 2b-Related Protein antibodyAnti-P15ink4b-Related Protein antibodyAnti-RPRD1A antibodyAnti-P15RS antibody |
Information sourced from Uniprot.org