• Western blot analysis of various lysates using RPRD1A Rabbit polyclonal antibody (STJ118299) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-RPRD1A antibody (47-276) (STJ118299)

SKU:
STJ118299

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RPRD1A (47-276) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RPRD1A
Gene ID: 55197
Uniprot ID: RPR1A_HUMAN
Immunogen Region: 47-276
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 47-276 of human RPRD1A (NP_001290341.1).
Immunogen Sequence: PVIVEAFKHVSSETDESCKK HLGRVLSIWEERSVYENDVL EQLKQALYGDKKPRKRTYEQ IKVDENENCSSLGSPSEPPQ TLDLVRALQDLENAASGDAA VHQRIASLPVEVQEVSLLDK ITDKESGERLSKMVEDACML LADYNGRLAAEIDDRKQLTR MLADFLRCQKEALAEKEHKL EEYKRKLARVSLVRKELRSR IQSLPDLSRLPNVTGSHMHL PFAGDIYSED
Function Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
Protein Name Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1a
Cyclin-Dependent Kinase Inhibitor 2b-Related Protein
P15ink4b-Related Protein
Database Links Reactome: R-HSA-6807505
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1a antibody
Anti-Cyclin-Dependent Kinase Inhibitor 2b-Related Protein antibody
Anti-P15ink4b-Related Protein antibody
Anti-RPRD1A antibody
Anti-P15RS antibody

Information sourced from Uniprot.org

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