Anti-RPN2 antibody (STJA0007720)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RPN2
General Information
| Short Description | Rabbit polyclonal anti-Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPN2 |
| Gene ID | 6185 |
| Uniprot ID | RPN2_HUMAN |
| Immunogen | Synthesized peptide derived from human RPN2 |
| Specificity | This antibody detects endogenous levels of RPN2 at Human, Mouse, Rat |
Additional Info
| Function | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. |
| Protein Name | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 2Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 Kda SubunitRibiirRibophorin IiRpn-IiRibophorin-2 |
| Database Links | Reactome: R-HSA-1799339Reactome: R-HSA-446203Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic ReticulumEndoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 2 antibodyAnti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 Kda Subunit antibodyAnti-Ribiir antibodyAnti-Ribophorin Ii antibodyAnti-Rpn-Ii antibodyAnti-Ribophorin-2 antibodyAnti-RPN2 antibody |
Information sourced from Uniprot.org