Anti-RPLP1 antibody (1-114) (STJ28808)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ28808
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General Information

Short DescriptionRabbit polyclonal RPLP1 (1-114) antibody for use in WB, IF, ICC and ELISA in human, mouse, rat and zebrafish samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat/Zebrafish
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
IF/ICC:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolRPLP1
Gene ID6176
Uniprot IDRLA1_HUMAN
Immunogen Region1-114
Immunogen SequenceMASVSELACIYSALILHDDE VTVTEDKINALIKAAGVNVE PFWPGLFAKALANVNIGSLI CNVGAGGPAPAAGAAPAGGP APSTAAAPAEEKKVEAKKEE SEESDDDMGFGLFD
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human RPLP1 (NP_000994.1).

Additional Info

Post Translational Modifications Ubiquitinated at Lys-92 and Lys-93 by RNF14 and RNF25 in response to ribosome collisions (ribosome stalling).
Function Plays an important role in the elongation step of protein synthesis.
Protein Name Large Ribosomal Subunit Protein P1
60s Acidic Ribosomal Protein P1
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-156902
Reactome: R-HSA-1799339
Reactome: R-HSA-192823
Reactome: R-HSA-2408557
Reactome: R-HSA-6791226
Reactome: R-HSA-72689
Reactome: R-HSA-72706
Reactome: R-HSA-72764
Reactome: R-HSA-9010553
Reactome: R-HSA-9633012
Reactome: R-HSA-975956
Reactome: R-HSA-975957
Cellular Localisation
Alternative Antibody Names Anti-Large Ribosomal Subunit Protein P1 antibody
Anti-60s Acidic Ribosomal Protein P1 antibody
Anti-RPLP1 antibody
Anti-RRP1 antibody

Information sourced from Uniprot.org

Citations

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