Anti-RPL3 antibody (1-260) (STJ29053)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RPL3 (1-260) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPL3 |
| Gene ID | 6122 |
| Uniprot ID | RL3_HUMAN |
| Immunogen Region | 1-260 |
| Immunogen Sequence | MSHRKFSAPRHGSLGFLPRK RSSRHRGKVKSFPKDDPSKP VHLTAFLGYKAGMTHIVREV DRPGSKVNKKEVVEAVTIVE TPPMVVVGIVGYVETPRGLR TFKTVFAEHISDECKRRFYK NWHKSKKKAFTKYCKKWQDE DGKKQLEKDFSSMKKYCQVI RVIAHTQMRLLPLRQKKAHL MEIQVNGGTVAEKLDWARER LEQQVPVNQVFGQDEMIDVI GVTKGKGYKGVTSRWHTKK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RPL3 (NP_000958.1). |
Additional Info
| Post Translational Modifications | Constitutively monomethylated at His-245 by METTL18. Methylation at His-245 regulates translation elongation by slowing ribosome traversal on tyrosine codons: slower elongation provides enough time for proper folding of synthesized proteins and prevents cellular aggregation of tyrosine-rich proteins. It is not required for incorporation of RPL3 into ribosomes. |
| Function | Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. |
| Protein Name | Large Ribosomal Subunit Protein Ul360s Ribosomal Protein L3Hiv-1 Tar Rna-Binding Protein BTarbp-B |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72689Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | NucleusNucleolusCytoplasm |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ul3 antibodyAnti-60s Ribosomal Protein L3 antibodyAnti-Hiv-1 Tar Rna-Binding Protein B antibodyAnti-Tarbp-B antibodyAnti-RPL3 antibodyAnti-OK antibodyAnti-SW-cl.32 antibody |
Information sourced from Uniprot.org