| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Large ribosomal subunit protein eL13 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPL13 |
| Gene ID: | 6137 |
| Uniprot ID: | RL13_HUMAN |
| Specificity: | This antibody detects endogenous levels of RPL13 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human RPL13 |
| Function | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs. Plays a role in bone development. |
| Protein Name | Large Ribosomal Subunit Protein El13 60s Ribosomal Protein L13 Breast Basic Conserved Protein 1 |
| Database Links | Reactome: R-HSA-156827 Reactome: R-HSA-156902 Reactome: R-HSA-1799339 Reactome: R-HSA-192823 Reactome: R-HSA-2408557 Reactome: R-HSA-6791226 Reactome: R-HSA-72689 Reactome: R-HSA-72706 Reactome: R-HSA-72764 Reactome: R-HSA-9010553 Reactome: R-HSA-9633012 Reactome: R-HSA-975956 Reactome: R-HSA-975957 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein El13 antibody Anti-60s Ribosomal Protein L13 antibody Anti-Breast Basic Conserved Protein 1 antibody Anti-RPL13 antibody Anti-BBC1 antibody Anti-OK antibody Anti-SW-cl.46 antibody |
Information sourced from Uniprot.org