| Short Description : | Rabbit polyclonal RPL13 (1-211) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPL13 |
| Gene ID: | 6137 |
| Uniprot ID: | RL13_HUMAN |
| Immunogen Region: | 1-211 |
| Immunogen Sequence: | MAPSRNGMVLKPHFHKDWQR RVATWFNQPARKIRRRKARQ AKARRIAPRPASGPIRPIVR CPTVRYHTKVRAGRGFSLEE LRVAGIHKKVARTIGISVDP RRRNKSTESLQANVQRLKEY RSKLILFPRKPSAPKKGDSS AEELKLATQLTGPVMPVRNV YKKEKARVITEEEKNFKAFA SLRMARANARLFGIRAKRAK EAAEQDVEKKK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human RPL13 (NP_150254.1). |
| Tissue Specificity | Higher levels of expression in benign breast lesions than in carcinomas. |
| Function | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs. Plays a role in bone development. |
| Protein Name | Large Ribosomal Subunit Protein El1360s Ribosomal Protein L13Breast Basic Conserved Protein 1 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72689Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein El13 antibodyAnti-60s Ribosomal Protein L13 antibodyAnti-Breast Basic Conserved Protein 1 antibodyAnti-RPL13 antibodyAnti-BBC1 antibodyAnti-OK antibodyAnti-SW-cl.46 antibody |
Information sourced from Uniprot.org
