| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein fantom is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RPGRIP1L |
| Gene ID: |
23322 |
| Uniprot ID: |
FTM_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RPGRIP1L at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human RPGRIP1L |
| Function | Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis. Involved in the organization of apical junctions.the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis. Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins. Involved in regulation of proteasomal activity at the primary cilium probably implicating association with PSDM2. |
| Protein Name | Protein FantomNephrocystin-8Rpgr-Interacting Protein 1-Like ProteinRpgrip1-Like Protein |
| Database Links | Reactome: R-HSA-5610787Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal BodyCilium AxonemeMicrotubule Organizing CenterCentrosomeCell JunctionTight JunctionIn Cultured Renal CellsIt Localizes Diffusely In The Cytoplasm ButAs Cells Approach ConfluenceIt Accumulates To Basolateral Tight JunctionsLocalizes To The Ciliary Transition Zone |
| Alternative Antibody Names | Anti-Protein Fantom antibodyAnti-Nephrocystin-8 antibodyAnti-Rpgr-Interacting Protein 1-Like Protein antibodyAnti-Rpgrip1-Like Protein antibodyAnti-RPGRIP1L antibodyAnti-FTM antibodyAnti-KIAA1005 antibodyAnti-NPHP8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
