Anti-ROR2 antibody (100-200) (STJ27587)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ROR2 (100-200) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ROR2 |
| Gene ID | 4920 |
| Uniprot ID | ROR2_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | APVVQEPRRIIIRKTEYGSR LRIQDLDTTDTGYYQCVATN GMKTITATGVLFVRLGPTHS PNHNFQDDYHEDGFCQPYRG IACARFIGNRTIYVDSLQMQ G |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ROR2 (NP_004551.2). |
Additional Info
| Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. |
| Protein Name | Tyrosine-Protein Kinase Transmembrane Receptor Ror2Neurotrophic Tyrosine Kinase - Receptor-Related 2 |
| Database Links | Reactome: R-HSA-4086400Reactome: R-HSA-5140745 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Transmembrane Receptor Ror2 antibodyAnti-Neurotrophic Tyrosine Kinase - Receptor-Related 2 antibodyAnti-ROR2 antibodyAnti-NTRKR2 antibody |
Information sourced from Uniprot.org