• Western blot analysis of extracts of various cell lines, using ROR2 Rabbit monoclonal antibody (STJ11102262) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-ROR2 antibody (1-100) [S2MR] (STJ11102262)

SKU:
STJ11102262

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-ROR2 (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S2MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ROR2
Gene ID: 4920
Uniprot ID: ROR2_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ROR2 (Q01974).
Immunogen Sequence: MARGSALPRRPLLCIPAVWA AAALLLSVSRTSGEVEVLDP NDPLGPLDGQDGPIPTLKGY FLNFLEPVNNITIVQGQTAI LHCKVAGNPPPNVRWLKNDA
Function Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.
Protein Name Tyrosine-Protein Kinase Transmembrane Receptor Ror2
Neurotrophic Tyrosine Kinase - Receptor-Related 2
Database Links Reactome: R-HSA-4086400
Reactome: R-HSA-5140745
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Tyrosine-Protein Kinase Transmembrane Receptor Ror2 antibody
Anti-Neurotrophic Tyrosine Kinase - Receptor-Related 2 antibody
Anti-ROR2 antibody
Anti-NTRKR2 antibody

Information sourced from Uniprot.org

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