Anti-ROMO1 antibody [SRM14990] (STJ11109720)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal ROMO1 antibody for use in WB, IF, ICC, IF-F, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-F/IF-P/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14990 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:14000-1:56000IF/ICC, 1:200-1:400IF-F, 1:200-1:400IF-P, 1:200-1:400IHC-P, 1:400-1:1600ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ROMO1 |
| Gene ID | 140823 |
| Uniprot ID | ROMO1_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line. Highly expressed in brain tumors. |
| Function | Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage. |
| Protein Name | Reactive Oxygen Species Modulator 1Ros Modulator 1Epididymis Tissue Protein Li 175GlyrichinMitochondrial Targeting Gxxxg Motif ProteinMtgmProtein Mgr2 Homolog |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Reactive Oxygen Species Modulator 1 antibodyAnti-Ros Modulator 1 antibodyAnti-Epididymis Tissue Protein Li 175 antibodyAnti-Glyrichin antibodyAnti-Mitochondrial Targeting Gxxxg Motif Protein antibodyAnti-Mtgm antibodyAnti-Protein Mgr2 Homolog antibodyAnti-ROMO1 antibodyAnti-C20orf52 antibody |
Information sourced from Uniprot.org