| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-RNF35/TRIM40 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.5-2µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
TRIM40 |
| Gene ID: |
135644 |
| Uniprot ID: |
TRI40_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_619645.1 |
| Immunogen Sequence: |
GVSELLLQPPQKL |
| Function | E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response. Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation. Promotes also the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation. |
| Protein Name | E3 Ubiquitin Ligase Trim40Probable E3 Nedd8-Protein LigaseRing Finger Protein 35 |
| Alternative Antibody Names | Anti-E3 Ubiquitin Ligase Trim40 antibodyAnti-Probable E3 Nedd8-Protein Ligase antibodyAnti-Ring Finger Protein 35 antibodyAnti-TRIM40 antibodyAnti-RNF35 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
