• Western blot analysis of various lysates using RNASEH2C Rabbit polyclonal antibody (STJ115823) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-RNASEH2C antibody (1-164) (STJ115823)

SKU:
STJ115823

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RNASEH2C (1-164) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RNASEH2C
Gene ID: 84153
Uniprot ID: RNH2C_HUMAN
Immunogen Region: 1-164
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human RNASEH2C (NP_115569.2).
Immunogen Sequence: MESGDEAAIERHRVHLRSAT LRDAVPATLHLLPCEVAVDG PAPVGRFFTPAIRQGPEGLE VSFRGRCLRGEEVAVPPGLV GYVMVTEEKKVSMGKPDPLR DSGTDDQEEEPLERDFDRFI GATANFSRFTLWGLETIPGP DAKVRGALTWPSLAAAIHAQ VPED
Tissue Specificity Widely expressed.
Function Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Protein Name Ribonuclease H2 Subunit C
Rnase H2 Subunit C
Aicardi-Goutieres Syndrome 3 Protein
Ags3
Rnase H1 Small Subunit
Ribonuclease Hi Subunit C
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ribonuclease H2 Subunit C antibody
Anti-Rnase H2 Subunit C antibody
Anti-Aicardi-Goutieres Syndrome 3 Protein antibody
Anti-Ags3 antibody
Anti-Rnase H1 Small Subunit antibody
Anti-Ribonuclease Hi Subunit C antibody
Anti-RNASEH2C antibody
Anti-AYP1 antibody

Information sourced from Uniprot.org

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