Anti-RNASEH2B antibody (STJA0008066)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RNASEH2B
General Information
| Short Description | Rabbit polyclonal anti-Ribonuclease H2 subunit B for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RNASEH2B |
| Gene ID | 79621 |
| Uniprot ID | RNH2B_HUMAN |
| Immunogen | Synthesized peptide derived from human RNASEH2B |
| Specificity | This antibody detects endogenous levels of RNASEH2B at Human, Mouse, Rat |
Additional Info
| Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
| Protein Name | Ribonuclease H2 Subunit BRnase H2 Subunit BAicardi-Goutieres Syndrome 2 ProteinAgs2Deleted In Lymphocytic Leukemia 8Ribonuclease Hi Subunit B |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ribonuclease H2 Subunit B antibodyAnti-Rnase H2 Subunit B antibodyAnti-Aicardi-Goutieres Syndrome 2 Protein antibodyAnti-Ags2 antibodyAnti-Deleted In Lymphocytic Leukemia 8 antibodyAnti-Ribonuclease Hi Subunit B antibodyAnti-RNASEH2B antibodyAnti-DLEU8 antibody |
Information sourced from Uniprot.org