Anti-RNASEH1 antibody (STJA0006766)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RNASEH1
General Information
| Short Description | Rabbit polyclonal anti-Ribonuclease H1 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RNASEH1 |
| Gene ID | 246243 |
| Uniprot ID | RNH1_HUMAN |
| Immunogen | Synthesized peptide derived from human RNASEH1 |
| Specificity | This antibody detects endogenous levels of RNASEH1 at Human, Rat |
Additional Info
| Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. |
| Protein Name | Ribonuclease H1Rnase H1Ribonuclease H Type Ii |
| Database Links | Reactome: R-HSA-9913635 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ribonuclease H1 antibodyAnti-Rnase H1 antibodyAnti-Ribonuclease H Type Ii antibodyAnti-RNASEH1 antibodyAnti-RNH1 antibody |
Information sourced from Uniprot.org