Anti-RMI2 antibody (73-123 aa) (STJ193992)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human RMI2 at the amino acid range 73-123
General Information
| Short Description | Rabbit polyclonal anti-RecQ-mediated genome instability protein 2 (73-123 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RMI2 |
| Gene ID | 116028 |
| Uniprot ID | RMI2_HUMAN |
| Immunogen | Synthesized peptide derived from the human RMI2 at the amino acid range 73-123 |
| Immunogen Region | 73-123 aa |
| Specificity | This antibody detects endogenous levels of RMI2 at Human/Mouse |
Additional Info
| Function | Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM. |
| Protein Name | Recq-Mediated Genome Instability Protein 2Hrmi2Blm-Associated Protein Of 18 KdaBlap18 |
| Database Links | Reactome: R-HSA-5685938Reactome: R-HSA-5685942Reactome: R-HSA-5693554Reactome: R-HSA-5693568Reactome: R-HSA-5693579Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-6804756Reactome: R-HSA-69473Reactome: R-HSA-9701192Reactome: R-HSA-9704331Reactome: R-HSA-9704646Reactome: R-HSA-9709570Reactome: R-HSA-9709603 |
| Cellular Localisation | NucleusColocalizes With Blm At Nuclear Dna Repair Foci |
| Alternative Antibody Names | Anti-Recq-Mediated Genome Instability Protein 2 antibodyAnti-Hrmi2 antibodyAnti-Blm-Associated Protein Of 18 Kda antibodyAnti-Blap18 antibodyAnti-RMI2 antibodyAnti-C16orf75 antibody |
Information sourced from Uniprot.org