• Western blot analysis of extracts of various cell lines, using RMI1 Antibody (STJ25361) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-RMI1 antibody (1-350) (STJ25361)

SKU:
STJ25361

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RMI1 (1-350) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RMI1
Gene ID: 80010
Uniprot ID: RMI1_HUMAN
Immunogen Region: 1-350
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RMI1 (NP_079221.2).
Immunogen Sequence: MNVTSIALRAETWLLAAWHV KVPPMWLEACINWIQEENNN VNLSQAQMNKQVFEQWLLTD LRDLEHPLLPDGILEIPKGE LNGFYALQINSLVDVSQPAY SQIQKLRGKNTTNDLVTAEA QVTPKPWEAKPSRMLMLQLT DGIVQIQGMEYQPIPILHSD LPPGTKILIYGNISFRLGVL LLKPENVKVLGGEVDALLEE YAQEKVLARLIGEPDLVVSV IPNNSNENIPRVTDVLDPA
Function Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
Protein Name Recq-Mediated Genome Instability Protein 1
Blm-Associated Protein Of 75 Kda
Blap75
Faap75
Database Links Reactome: R-HSA-5685938
Reactome: R-HSA-5685942
Reactome: R-HSA-5693554
Reactome: R-HSA-5693568
Reactome: R-HSA-5693579
Reactome: R-HSA-5693607
Reactome: R-HSA-5693616
Reactome: R-HSA-6804756
Reactome: R-HSA-69473
Reactome: R-HSA-9701192
Reactome: R-HSA-9704331
Reactome: R-HSA-9704646
Reactome: R-HSA-9709570
Reactome: R-HSA-9709603
Cellular Localisation Nucleus
Forms Foci In Response To Dna Damage
Alternative Antibody Names Anti-Recq-Mediated Genome Instability Protein 1 antibody
Anti-Blm-Associated Protein Of 75 Kda antibody
Anti-Blap75 antibody
Anti-Faap75 antibody
Anti-RMI1 antibody
Anti-C9orf76 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance