Anti-RLBP1 antibody (1-317) (STJ111562)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RLBP1 (1-317) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RLBP1 |
| Gene ID | 6017 |
| Uniprot ID | RLBP1_HUMAN |
| Immunogen Region | 1-317 |
| Immunogen Sequence | MSEGVGTFRMVPEEEQELRA QLEQLTTKDHGPVFGPCSQL PRHTLQKAKDELNEREETRE EAVRELQEMVQAQAASGEEL AVAVAERVQEKDSGFFLRFI RARKFNVGRAYELLRGYVNF RLQYPELFDSLSPEAVRCTI EAGYPGVLSSRDKYGRVVML FNIENWQSQEITFDEILQAY CFILEKLLENEETQINGFCI IENFKGFTMQQAASLRTSDL RKMVDMLQDSFPARFKAIH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human CRALBP (NP_000317.1). |
Additional Info
| Tissue Specificity | Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina. |
| Function | Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. |
| Protein Name | Retinaldehyde-Binding Protein 1Cellular Retinaldehyde-Binding Protein |
| Database Links | Reactome: R-HSA-2187335Reactome: R-HSA-2453902Reactome: R-HSA-9918438 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Retinaldehyde-Binding Protein 1 antibodyAnti-Cellular Retinaldehyde-Binding Protein antibodyAnti-RLBP1 antibodyAnti-CRALBP antibody |
Information sourced from Uniprot.org