Anti-RKIP antibody [R09-3K3] (STJA0036002)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human PEBP1
General Information
| Short Description | Rabbit monoclonal anti-RKIP for use in WB, IHC-P, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R09-3K3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:20 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PEBP1 |
| Gene ID | 5037 |
| Uniprot ID | PEBP1_HUMAN |
| Immunogen | A synthesized peptide derived from human PEBP1 |
Additional Info
| Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. |
| Protein Name | Phosphatidylethanolamine-Binding Protein 1Pebp-1HcnpppNeuropolypeptide H3Prostatic-Binding ProteinRaf Kinase Inhibitor ProteinRkip Cleaved Into - Hippocampal Cholinergic Neurostimulating PeptideHcnp |
| Database Links | Reactome: R-HSA-5674135Reactome: R-HSA-5675221Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-9649948 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Phosphatidylethanolamine-Binding Protein 1 antibodyAnti-Pebp-1 antibodyAnti-Hcnppp antibodyAnti-Neuropolypeptide H3 antibodyAnti-Prostatic-Binding Protein antibodyAnti-Raf Kinase Inhibitor Protein antibodyAnti-Rkip Cleaved Into - Hippocampal Cholinergic Neurostimulating Peptide antibodyAnti-Hcnp antibodyAnti-PEBP1 antibodyAnti-PBP antibodyAnti-PEBP antibody |
Information sourced from Uniprot.org