Anti-RIPK4 antibody (240-520) (STJ110793)

Name: Anti-RIPK4 antibody (240-520) (STJ110793)
SKU: STJ110793
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ110793

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Short Description	Rabbit polyclonal RIPK4 (240-520) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:100-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	RIPK4Uniprot ID=RIPK4_HUMAN"
Immunogen Region	240-520
Immunogen Sequence	HRPELPPVCRARPRACSHLI RLMQRCWQGDPRVRPTFQEI TSETEDLCEKPDDEVKETAH DLDVKSPPEPRSEVVPARLK RASAPTFDNDYSLSELLSQL DSGVSQAVEGPEELSRSSSE SKLPSSGSGKRLSGVSSVDS AFSSRGSLSLSFEREPSTSD LGTTDVQKKKLVDAIVSGDT SKLMKILQPQDVDLALDSGA SLLHLAVEAGQEECAKWLLL NNANPNLSNRRGSTPLHMA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2).

Tissue Specificity	Expressed in hair follicles and skin.
Post Translational Modifications	May be phosphorylated by MAP3K2 and MAP3K3. Proteolytically cleaved by during Fas-induced apoptosis. Cleavage at Asp-388 and Asp-426. Polyubiquitinated with 'Lys-48' and 'Lys-63'-linked chains by BIRC2/c-IAP1 and BIRC3/c-IAP2, leading to activation of NF-kappa-B.
Function	Serine/threonine protein kinase. Required for embryonic skin development and correct skin homeostasis in adults, via phosphorylation of PKP1 and subsequent promotion of keratinocyte differentiation and cell adhesion. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.
Protein Name	Receptor-Interacting Serine/Threonine-Protein Kinase 4 Ankyrin Repeat Domain-Containing Protein 3 Pkc-Delta-Interacting Protein Kinase
Cellular Localisation	Cytoplasm Membrane Peripheral Membrane Protein
Alternative Antibody Names	Anti-Receptor-Interacting Serine/Threonine-Protein Kinase 4 antibody Anti-Ankyrin Repeat Domain-Containing Protein 3 antibody Anti-Pkc-Delta-Interacting Protein Kinase antibody Anti-RIPK4 antibody Anti-ANKRD3 antibody Anti-DIK antibody

Information sourced from Uniprot.org