Anti-RIN2 antibody (596-895) (STJ115742)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RIN2 (596-895) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RIN2 |
| Gene ID | 54453 |
| Uniprot ID | RIN2_HUMAN |
| Immunogen Region | 596-895 |
| Immunogen Sequence | HKCILKPLKGHVEAMLKDFH MADGSWKQLKENLQLVRQRN PQELGVFAPTPDFVDVEKIK VKFMTMQKMYSPEKKVMLLL RVCKLIYTVMENNSGRMYGA DDFLPVLTYVIAQCDMLELD TEIEYMMELLDPSLLHGEGG YYLTSAYGALSLIKNFQEEQ AARLLSSETRDTLRQWHKRR TTNRTIPSVDDFQNYLRVAF QEVNSGCTGKTLLVRPYITT EDVCQICAEKFKVGDPEEY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1). |
Additional Info
| Tissue Specificity | Widely expressed. Expressed in heart, kidney, lung placenta. Expressed at low level in skeletal muscle, spleen and peripheral blood. |
| Function | Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP. |
| Protein Name | Ras And Rab Interactor 2Ras Association Domain Family 4Ras Inhibitor Jc265Ras Interaction/Interference Protein 2 |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ras And Rab Interactor 2 antibodyAnti-Ras Association Domain Family 4 antibodyAnti-Ras Inhibitor Jc265 antibodyAnti-Ras Interaction/Interference Protein 2 antibodyAnti-RIN2 antibodyAnti-RASSF4 antibody |
Information sourced from Uniprot.org