Anti-RIC3 antibody (STJA0008064)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RIC3
General Information
| Short Description | Rabbit polyclonal anti-Protein RIC-3 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RIC3 |
| Gene ID | 79608 |
| Uniprot ID | RIC3_HUMAN |
| Immunogen | Synthesized peptide derived from human RIC3 |
| Specificity | This antibody detects endogenous levels of RIC3 at Human, Mouse |
Additional Info
| Function | Molecular chaperone which facilitates proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) and alpha-8 (CHRNA8) nicotinic acetylcholine receptors. May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4. |
| Protein Name | Protein Ric-3Resistant To Inhibitor Of Cholinesterase 3 |
| Database Links | |
| Cellular Localisation | Isoform 1: Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinIsoform 2: Endoplasmic Reticulum MembraneGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Protein Ric-3 antibodyAnti-Resistant To Inhibitor Of Cholinesterase 3 antibodyAnti-RIC3 antibodyAnti-UNQ720 antibodyAnti-PRO1385 antibody |
Information sourced from Uniprot.org