| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Mitochondrial Rho GTPase 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RHOT2 |
| Gene ID: | 89941 |
| Uniprot ID: | MIRO2_HUMAN |
| Specificity: | This antibody detects endogenous levels of MIRO2 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human MIRO2 |
| Post Translational Modifications | Ubiquitinated by PRKN in a PINK1-dependent manner, leading to its degradation. |
| Function | Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Can hydrolyze GTP. Can hydrolyze ATP and UTP. |
| Protein Name | Mitochondrial Rho Gtpase 2Miro-2Hmiro-2Ras Homolog Gene Family Member T2 |
| Database Links | Reactome: R-HSA-9013419 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinColocalizes With Mgarp And Rhot2 At The Mitochondria |
| Alternative Antibody Names | Anti-Mitochondrial Rho Gtpase 2 antibodyAnti-Miro-2 antibodyAnti-Hmiro-2 antibodyAnti-Ras Homolog Gene Family Member T2 antibodyAnti-RHOT2 antibodyAnti-ARHT2 antibodyAnti-C16orf39 antibody |
Information sourced from Uniprot.org
