Anti-RHOC antibody (STJA0006810)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RHOC
General Information
| Short Description | Rabbit polyclonal anti-Rho-related GTP-binding protein RhoC for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RHOC |
| Gene ID | 389 |
| Uniprot ID | RHOC_HUMAN |
| Immunogen | Synthesized peptide derived from human RHOC |
| Specificity | This antibody detects endogenous levels of RHOC at Human, Mouse |
Additional Info
| Function | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells. |
| Protein Name | Rho-Related Gtp-Binding Protein RhocRho Cdna Clone 9H9 |
| Database Links | Reactome: R-HSA-416482Reactome: R-HSA-416572Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5663220Reactome: R-HSA-5666185Reactome: R-HSA-9013106 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCleavage FurrowTranslocates To The Equatorial Region Before Furrow Formation In A Ect2-Dependent Manner |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhoc antibodyAnti-Rho Cdna Clone 9 antibodyAnti-H9 antibodyAnti-RHOC antibodyAnti-ARH9 antibodyAnti-ARHC antibody |
Information sourced from Uniprot.org