• Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100
  • Western blot analysis of extracts from Jurkat, K562 cells, using RhCG Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-RHCG antibody (Internal) (STJ96453)

SKU:
STJ96453

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ammonium transporter Rh type C (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RHCG
Gene ID: 51458
Uniprot ID: RHCG_HUMAN
Immunogen Region: Internal
Specificity: RhCG Polyclonal Antibody detects endogenous levels of RhCG protein.
Immunogen: Synthesized peptide derived from the Internal region of human RhCG.
Post Translational Modifications N-glycosylated.
Function Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. Postulated to primarily mediate an electroneutral bidirectional transport of NH3 ammonia species according to a mechanism that implies interaction of an NH4(+) ion with acidic residues of the pore entry followed by dissociation of NH4(+) into NH3 and H(+). As a result NH3 transits through the central pore and is protonated on the extracellular side reforming NH4(+). May act as a CO2 channel providing for renal acid secretion.
Protein Name Ammonium Transporter Rh Type C
Rh Glycoprotein Kidney
Rhesus Blood Group Family Type C Glycoprotein
Rh Family Type C Glycoprotein
Rh Type C Glycoprotein
Tumor-Related Protein Drc2
Database Links Reactome: R-HSA-444411
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Also Detected At The Basolateral Membrane And In Subapical Vesicles
Alternative Antibody Names Anti-Ammonium Transporter Rh Type C antibody
Anti-Rh Glycoprotein Kidney antibody
Anti-Rhesus Blood Group Family Type C Glycoprotein antibody
Anti-Rh Family Type C Glycoprotein antibody
Anti-Rh Type C Glycoprotein antibody
Anti-Tumor-Related Protein Drc2 antibody
Anti-RHCG antibody
Anti-C15orf6 antibody
Anti-CDRC2 antibody
Anti-PDRC2 antibody
Anti-RHGK antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance