| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-RHBDF2 (800-850) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | ~0.50-0.75 µg/µl |
| Dilution Range: | WB: 1:500-1:5, 000ELISA: 1:50, 000IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | RHBDF2 |
| Gene ID: | 79651 |
| Uniprot ID: | RHDF2_HUMAN |
| Immunogen Region: | 800-850 |
| Immunogen: | Synthetic peptide taken within amino aid region 800-850 on human Inactive rhomboid protein 2. |
| Tissue Specificity | Found in the epidermis and esophageal epithelium. |
| Function | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. |
| Protein Name | Inactive Rhomboid Protein 2Irhom2Rhomboid 5 Homolog 2Rhomboid Family Member 2Rhomboid Veinlet-Like Protein 5Rhomboid Veinlet-Like Protein 6 |
| Database Links | Reactome: R-HSA-9662834 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Inactive Rhomboid Protein 2 antibodyAnti-Irhom2 antibodyAnti-Rhomboid 5 Homolog 2 antibodyAnti-Rhomboid Family Member 2 antibodyAnti-Rhomboid Veinlet-Like Protein 5 antibodyAnti-Rhomboid Veinlet-Like Protein 6 antibodyAnti-RHBDF2 antibodyAnti-IRHOM2 antibodyAnti-RHBDL5 antibodyAnti-RHBDL6 antibody |
Information sourced from Uniprot.org