| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RHBDF1 (200-400) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RHBDF1 |
| Gene ID: |
64285 |
| Uniprot ID: |
RHDF1_HUMAN |
| Immunogen Region: |
200-400 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human RHBDF1 (NP_071895.3). |
| Immunogen Sequence: |
HRLPRRRKRESVAKMSFRAA AALMKGRSVRDGTFRRAQRR SFTPASFLEEDTTDFPDELD TSFFAREGILHEELSTYPDE VFESPSEAALKDWEKAPEQA DLTGGALDRSELERSHLMLP LERGWRKQKEGAAAPQPKVR LRQEVVSTAGPRRGQRIAVP VRKLFAREKRPYGLGMVGRL TNRTYRKRIDSFVKRQIEDM D |
| Tissue Specificity | Highly expressed in cerebellum, cerebrum, heart, skeletal muscle, placenta, pancreatic islet and testis. Detected at lower levels in colon, kidney, small intestine and lung. |
| Post Translational Modifications | N-glycosylated. |
| Function | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. |
| Protein Name | Inactive Rhomboid Protein 1Irhom1Epidermal Growth Factor Receptor-Related ProteinRhomboid 5 Homolog 1Rhomboid Family Member 1P100hrho |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembranePredominantly Localized In The Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Inactive Rhomboid Protein 1 antibodyAnti-Irhom1 antibodyAnti-Epidermal Growth Factor Receptor-Related Protein antibodyAnti-Rhomboid 5 Homolog 1 antibodyAnti-Rhomboid Family Member 1 antibodyAnti-P100hrho antibodyAnti-RHBDF1 antibodyAnti-C16orf8 antibodyAnti-DIST1 antibodyAnti-IRHOM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
