Anti-RHAG antibody (1-50 aa) (STJ96649)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human RHAG at the amino acid range 1-50
General Information
| Short Description | Rabbit polyclonal anti-Ammonium transporter Rh type A (1-50 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RHAG |
| Gene ID | 6005 |
| Uniprot ID | RHAG_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human RHAG at the amino acid range 1-50 |
| Immunogen Region | 1-50 aa |
| Specificity | CD241 Polyclonal Antibody detects endogenous levels of CD241 protein. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Heterotrimer with RHCE (RHAG)2(RHCE), that transports ammonium and its related derivative methylammonium, in both neutral and ionic forms, across the erythrocyte membrane. The transport of NH4(+) is electrogenic and masks the NH3 transport. Also, may act as a CO2 channel. In vitro, leaks monovalent cations. Moreover in erythrocyte, regulates RHD membrane expression and is associated with rhesus blood group antigen expression. |
| Protein Name | Ammonium Transporter Rh Type AErythrocyte Membrane Glycoprotein Rh50Erythrocyte Plasma Membrane 50 Kda GlycoproteinRh50aRhesus Blood Group Family Type A GlycoproteinRh Family Type A GlycoproteinRh Type A GlycoproteinRhesus Blood Group-Associated Ammonia ChannelRhesus Blood Group-Associated GlycoproteinCd Antigen Cd241 |
| Database Links | Reactome: R-HSA-1237044Reactome: R-HSA-1247673Reactome: R-HSA-444411Reactome: R-HSA-5619042 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinLocalization At The Plasma Membrane Is Regulated By Ank1 |
| Alternative Antibody Names | Anti-Ammonium Transporter Rh Type A antibodyAnti-Erythrocyte Membrane Glycoprotein Rh50 antibodyAnti-Erythrocyte Plasma Membrane 50 Kda Glycoprotein antibodyAnti-Rh50a antibodyAnti-Rhesus Blood Group Family Type A Glycoprotein antibodyAnti-Rh Family Type A Glycoprotein antibodyAnti-Rh Type A Glycoprotein antibodyAnti-Rhesus Blood Group-Associated Ammonia Channel antibodyAnti-Rhesus Blood Group-Associated Glycoprotein antibodyAnti-Cd Antigen Cd241 antibodyAnti-RHAG antibodyAnti-RH50 antibody |
Information sourced from Uniprot.org