Anti-RGS3 antibody (STJA0009764)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RGS3
General Information
| Short Description | Rabbit polyclonal anti-Regulator of G-protein signaling 3 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RGS3 |
| Gene ID | 5998 |
| Uniprot ID | RGS3_HUMAN |
| Immunogen | Synthesized peptide derived from human RGS3 |
| Specificity | This antibody detects endogenous levels of RGS3 at Human, Mouse, Rat |
Additional Info
| Function | Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases. |
| Protein Name | Regulator Of G-Protein Signaling 3Rgp3Rgs3 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594 |
| Cellular Localisation | CytoplasmNucleusCell MembranePeripheral Membrane ProteinLong Isoforms Are Cytoplasmic And Associated With The Plasma MembraneShort Isoforms Are Nuclear |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 3 antibodyAnti-Rgp3 antibodyAnti-Rgs3 antibodyAnti-RGS3 antibody |
Information sourced from Uniprot.org