Anti-RGS16 antibody (141-190 aa) (STJ95439)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RGS16 at the amino acid range 141-190
General Information
| Short Description | Rabbit polyclonal anti-Regulator of G-protein signaling 16 (141-190 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RGS16 |
| Gene ID | 6004 |
| Uniprot ID | RGS16_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RGS16 at the amino acid range 141-190 |
| Immunogen Region | 141-190 aa |
| Specificity | RGS16 Polyclonal Antibody detects endogenous levels of RGS16 protein. |
Additional Info
| Post Translational Modifications | Palmitoylated on Cys-2 and/or Cys-12. Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1. |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals. |
| Protein Name | Regulator Of G-Protein Signaling 16Rgs16A28-Rgs14pRetinal-Specific RgsRgs-RHrgs-RRetinally Abundant Regulator Of G-Protein Signaling |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594Reactome: R-HSA-418597 |
| Cellular Localisation | MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 16 antibodyAnti-Rgs16 antibodyAnti-A28-Rgs14p antibodyAnti-Retinal-Specific Rgs antibodyAnti-Rgs-R antibodyAnti-Hrgs-R antibodyAnti-Retinally Abundant Regulator Of G-Protein Signaling antibodyAnti-RGS16 antibodyAnti-RGSR antibody |
Information sourced from Uniprot.org