| Host: | Rabbit |
| Applications: | WB/IF/ICC/IP/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RFC4 |
| Gene ID: | 5984 |
| Uniprot ID: | RFC4_HUMAN |
| Immunogen Region: | 204-363 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-363 of human RFC4 (NP_002907.1). |
| Immunogen Sequence: | DKIQQQRLLDIAKKENVKIS DEGIAYLVKVSEGDLRKAIT FLQSATRLTGGKEITEKVIT DIAGVIPAEKIDGVFAACQS GSFDKLEAVVKDLIDEGHAA TQLVNQLHDVVVENNLSDKQ KSIITEKLAEVDKCLADGAD EHLQLISLCATVMQQLSQNC |
| Function | The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template. |
| Protein Name | Replication Factor C Subunit 4Activator 1 37 Kda SubunitA1 37 Kda SubunitActivator 1 Subunit 4Replication Factor C 37 Kda SubunitRf-C 37 Kda SubunitRfc37 |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-110314Reactome: R-HSA-110320Reactome: R-HSA-174411Reactome: R-HSA-176187Reactome: R-HSA-5651801Reactome: R-HSA-5655862Reactome: R-HSA-5656121Reactome: R-HSA-5656169Reactome: R-HSA-5685938Reactome: R-HSA-5685942Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-5696397Reactome: R-HSA-5696400Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6804756Reactome: R-HSA-69091Reactome: R-HSA-69473Reactome: R-HSA-9709570 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Replication Factor C Subunit 4 antibodyAnti-Activator 1 37 Kda Subunit antibodyAnti-A1 37 Kda Subunit antibodyAnti-Activator 1 Subunit 4 antibodyAnti-Replication Factor C 37 Kda Subunit antibodyAnti-Rf-C 37 Kda Subunit antibodyAnti-Rfc37 antibodyAnti-RFC4 antibody |
Information sourced from Uniprot.org