| Short Description : | Rabbit polyclonal anti-DNA polymerase zeta catalytic subunit (231-280 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | REV3L |
| Gene ID: | 5980 |
| Uniprot ID: | REV3L_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DNA Polymerase zeta at the amino acid range 231-280 |
| Immunogen Region: | 231-280 aa |
| Specificity: | DNA pol Zeta Polyclonal Antibody detects endogenous levels of DNA pol Zeta protein. |
| Function | Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function. |
| Protein Name | Dna Polymerase Zeta Catalytic SubunitProtein Reversionless 3-LikeRev3-LikeHrev3 |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-5655862Reactome: R-HSA-5656121 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Polymerase Zeta Catalytic Subunit antibodyAnti-Protein Reversionless 3-Like antibodyAnti-Rev3-Like antibodyAnti-Hrev3 antibodyAnti-REV3L antibodyAnti-POLZ antibodyAnti-REV3 antibody |
Information sourced from Uniprot.org
