| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RERE (1-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RERE |
| Gene ID: |
473 |
| Uniprot ID: |
RERE_HUMAN |
| Immunogen Region: |
1-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RERE (NP_036234.3). |
| Immunogen Sequence: |
MTADKDKDKDKEKDRDRDRD REREKRDKARESENSRPRRS CTLEGGAKNYAESDHSEDED NDNNSATAEESTKKNKKKPP KKKSRYERTDTGEITSYITE DDVVYRPGDCVYIESRRPNT PYFICSIQDFKLVHNSQACC RSPTPALCDPPACSLPVASQ PPQHLSEAGRGPVGSKRDHL LMNVKWYYRQSEVPDSVYQH LVQDRHNENDSGRELVITDP |
| Tissue Specificity | Widely expressed. Expressed in tumor cell lines. |
| Function | Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. |
| Protein Name | Arginine-Glutamic Acid Dipeptide Repeats ProteinAtrophin-1-Like ProteinAtrophin-1-Related Protein |
| Cellular Localisation | NucleusLocalized In Nuclear Bodies Of Variables SizeColocalized With Pml And Bax In Nuclear Pods |
| Alternative Antibody Names | Anti-Arginine-Glutamic Acid Dipeptide Repeats Protein antibodyAnti-Atrophin-1-Like Protein antibodyAnti-Atrophin-1-Related Protein antibodyAnti-RERE antibodyAnti-ARG antibodyAnti-ARP antibodyAnti-ATN1L antibodyAnti-KIAA0458 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98774/382822/STJ119989_1__22320.1713151321.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")