Anti-REPS2 antibody (390-470 aa) (STJ191248)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 390-470
General Information
| Short Description | Rabbit polyclonal anti-RalBP1-associated Eps domain-containing protein 2 (390-470 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | REPS2 |
| Gene ID | 9185 |
| Uniprot ID | REPS2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 390-470 |
| Immunogen Region | 390-470 aa |
| Specificity | REPS2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Tyrosine-phosphorylated upon stimulation of cells with EGF. Phosphorylation on Tyr-residues induces its association with the EGF receptor probably indirectly through an adapter like GRB2. |
| Function | Involved in ligand-dependent receptor mediated endocytosis of the EGF and insulin receptors as part of the Ral signaling pathway. By controlling growth factor receptors endocytosis may regulate cell survival. Through ASAP1 may regulate cell adhesion and migration. |
| Protein Name | Ralbp1-Associated Eps Domain-Containing Protein 2Partner Of Ralbp1Ralbp1-Interacting Protein 2 |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ralbp1-Associated Eps Domain-Containing Protein 2 antibodyAnti-Partner Of Ralbp1 antibodyAnti-Ralbp1-Interacting Protein 2 antibodyAnti-REPS2 antibodyAnti-POB1 antibody |
Information sourced from Uniprot.org