Anti-REN antibody (1-100) [S0MR] (STJ11102290)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Renin (1-100) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S0MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | REN |
| Gene ID | 5972 |
| Uniprot ID | RENI_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MDGWRRMPRWGLLLLLWGSC TFGLPTDTTTFKRIFLKRMP SIRESLKERGVDMARLGPEW SQPMKRLTLGNTTSSVILTN YMDTQYYGEIGIGTPPQTFK |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Renin (P00797). |
Additional Info
| Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Protein Name | ReninAngiotensinogenase |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedMembraneAssociated To Membranes Via Binding To Atp6ap2 |
| Alternative Antibody Names | Anti-Renin antibodyAnti-Angiotensinogenase antibodyAnti-REN antibody |
Information sourced from Uniprot.org