Anti-REG4 antibody (23-158) (STJ115095)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal REG4 (23-158) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | REG4 |
| Gene ID | 83998 |
| Uniprot ID | REG4_HUMAN |
| Immunogen Region | 23-158 |
| Immunogen Sequence | DIIMRPSCAPGWFYHKSNCY GYFRKLRNWSDAELECQSYG NGAHLASILSLKEASTIAEY ISGYQRSQPIWIGLHDPQKR QQWQWIDGAMYLYRSWSGKS MGGNKHCAEMSSNNNFLTWS SNECNKRQHFLCKYRP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 23-158 of human REG4 (NP_114433.1). |
Additional Info
| Tissue Specificity | Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. |
| Function | Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. |
| Protein Name | Regenerating Islet-Derived Protein 4Reg-4Gastrointestinal Secretory ProteinReg-Like ProteinRegenerating Islet-Derived Protein IvReg Iv |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Regenerating Islet-Derived Protein 4 antibodyAnti-Reg-4 antibodyAnti-Gastrointestinal Secretory Protein antibodyAnti-Reg-Like Protein antibodyAnti-Regenerating Islet-Derived Protein Iv antibodyAnti-Reg Iv antibodyAnti-REG4 antibodyAnti-GISP antibodyAnti-RELP antibody |
Information sourced from Uniprot.org