• Western blot analysis of extracts of various cell lines, using REG1A antibody (STJ27280) at 1:1000 dilution. _Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. _Lysates/proteins: 25 Mu g per lane. _Blocking buffer: 3% nonfat dry milk in TBST. _Detection: ECL Basic Kit. _Exposure time: 60s.

Anti-REG1A antibody (50-150) (STJ27280)

SKU:
STJ27280

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-REG1A (50-150) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: REG1A
Gene ID: 5967
Uniprot ID: REG1A_HUMAN
Immunogen Region: 50-150
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human REG1A (NP_002900.2).
Immunogen Sequence: FNEDRETWVDADLYCQNMNS GNLVSVLTQAEGAFVASLIK ESGTDDFNVWIGLHDPKKNR RWHWSSGSLVSYKSWGIGAP SSVNPGYCVSLTSSTGFQKW K
Tissue Specificity In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients.
Post Translational Modifications The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine.
Function Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
Protein Name Lithostathine-1-Alpha
Islet Cells Regeneration Factor
Icrf
Islet Of Langerhans Regenerating Protein
Reg
Pancreatic Stone Protein
Psp
Pancreatic Thread Protein
Ptp
Regenerating Islet-Derived Protein 1-Alpha
Reg-1-Alpha
Regenerating Protein I Alpha
Cellular Localisation Secreted
Alternative Antibody Names Anti-Lithostathine-1-Alpha antibody
Anti-Islet Cells Regeneration Factor antibody
Anti-Icrf antibody
Anti-Islet Of Langerhans Regenerating Protein antibody
Anti-Reg antibody
Anti-Pancreatic Stone Protein antibody
Anti-Psp antibody
Anti-Pancreatic Thread Protein antibody
Anti-Ptp antibody
Anti-Regenerating Islet-Derived Protein 1-Alpha antibody
Anti-Reg-1-Alpha antibody
Anti-Regenerating Protein I Alpha antibody
Anti-REG1A antibody
Anti-PSPS antibody
Anti-PSPS1 antibody
Anti-REG antibody

Information sourced from Uniprot.org

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