Anti-REG1A antibody (50-150) (STJ27280)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal REG1A (50-150) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | REG1A |
| Gene ID | 5967 |
| Uniprot ID | REG1A_HUMAN |
| Immunogen Region | 50-150 |
| Immunogen Sequence | FNEDRETWVDADLYCQNMNS GNLVSVLTQAEGAFVASLIK ESGTDDFNVWIGLHDPKKNR RWHWSSGSLVSYKSWGIGAP SSVNPGYCVSLTSSTGFQKW K |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human REG1A (NP_002900.2). |
Additional Info
| Tissue Specificity | In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients. |
| Post Translational Modifications | The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine. |
| Function | Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. |
| Protein Name | Lithostathine-1-AlphaIslet Cells Regeneration FactorIcrfIslet Of Langerhans Regenerating ProteinRegPancreatic Stone ProteinPspPancreatic Thread ProteinPtpRegenerating Islet-Derived Protein 1-AlphaReg-1-AlphaRegenerating Protein I Alpha |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Lithostathine-1-Alpha antibodyAnti-Islet Cells Regeneration Factor antibodyAnti-Icrf antibodyAnti-Islet Of Langerhans Regenerating Protein antibodyAnti-Reg antibodyAnti-Pancreatic Stone Protein antibodyAnti-Psp antibodyAnti-Pancreatic Thread Protein antibodyAnti-Ptp antibodyAnti-Regenerating Islet-Derived Protein 1-Alpha antibodyAnti-Reg-1-Alpha antibodyAnti-Regenerating Protein I Alpha antibodyAnti-REG1A antibodyAnti-PSPS antibodyAnti-PSPS1 antibodyAnti-REG antibody |
Information sourced from Uniprot.org