Anti-RECQL4 antibody (231-330) (STJ28928)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RECQL4 (231-330) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RECQL4 |
| Gene ID | 9401 |
| Uniprot ID | RECQ4_HUMAN |
| Immunogen Region | 231-330 |
| Immunogen Sequence | GAGSQGPEASAFQEVSIRVG SPQPSSSGGEKRRWNEEPWE SPAQVQQESSQAGPPSEGAG AVAVEEDPPGEPVQAQPPQP CSSPSNPRYHGLSPSSQARA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 231-330 of human RECQL4 (NP_004251.3). |
Additional Info
| Tissue Specificity | Ubiquitously expressed, with highest levels in thymus and testis. |
| Function | An ATP-dependent DNA helicase which unwinds dsDNA with a 3'-overhang in a 3'-5' direction. Does not unwind more than 18 bp of dsDNA. May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA. The core helicase domain binds ssDNA. |
| Protein Name | Atp-Dependent Dna Helicase Q4Dna 3'-5' Helicase Recq4Dna Helicase - Recq-Like Type 4Recq4RtsRecq Protein-Like 4 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Atp-Dependent Dna Helicase Q4 antibodyAnti-Dna 3'-5' Helicase Recq4 antibodyAnti-Dna Helicase - Recq-Like Type 4 antibodyAnti-Recq4 antibodyAnti-Rts antibodyAnti-Recq Protein-Like 4 antibodyAnti-RECQL4 antibodyAnti-RECQ4 antibody |
Information sourced from Uniprot.org